| HelpRecID:
7 |
| QE-300.02
- Rate of Development |
2/6/30/7
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Question
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Is the rate of cleavage normal?
- [Question # QHE016] |
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Option
#1
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YES, this embryo is normal. |
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Option
#2
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No - this embryo has cleaved or developed faster than expected. |
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Option
#3
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No, the embryo is delayed. |
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Option
#4
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No, the embryo has arrested or significantly delayed. |
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Option
#5
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No, the embryo is abnormal. |
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Description
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Embryo development rates. |
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Comment
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The rate of development of an embryo will depend on both external factors ( IVF culture conditions) and intrinsic factors ( ATP levels, mitochondrial activity, genetic competency). Embryo development scale developed in the late 1980s can be used to provide a numeric probability of its development potential. Recent changes to culture systems may make such scales inappropriate and may need revision. If the examination of embryos is amde at the same time each day, each laboratory can develop a system for normal development. While selection of emrbyos for transfer remains the prime explantion for differences between clinics in their pregnancy rates, establishing standard rates eg % 4 cell embryos at say 44hr post insemination can develop over time as a powerful tool to monitor for laboratory quality and for the assessment of new culture conditions such as culture media. This question attempts to provide a mechanism for each embryologist to confirm the selection of embryos is consistent with others either in the same unit or elsewhere. It is easy to distinguish between a good embryo and a poor embryo but less easy to distinguish between good embryos. |
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Image
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Width=200 and Height=200 |
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References
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Sakkas,D (2001) :Evaulation of embryo quality: a stategy for sequential analysis of embryo development with the aim of single embryo transfer.
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